An Australian (1995) study found oxazepam less toxic and less sedative, and temazepam more toxic and more sedative, than most benzodiazepines in overdose. Temazepam was shown to be more toxic than the majority of benzodiazepines. 2010 Top 200 (brand, generic, & drug class) top 200 drugs for a pharmacy tech exam. Over 10 years in the United Kingdom, 1512 fatal poisonings have been attributed to benzodiazepines with or without alcohol. A set of Top 200, generic, brand, classification, drug form and stability. Benzodiazepines are one of the most highly prescribed classes of drugs, and they are commonly used in self-poisoning. Study with Quizlet and memorize flashcards containing terms like D Flumazenil is the antidote for benzodiazepine overdose. There is an antidote, flumazenil, but its use is controversial. Physostigmine is a safe and effective antidote for anticholinergic poisoning. Recent internet phenomenon have led to increased misuse of diphenhydramine especially among adolescents. The US Food and Drug Administration (FDA) has subsequently issued a black box warning regarding concurrent use of benzodiazepines and opioids. Supportive care is the mainstay of treatment of benzodiazepine overdose. Diphenhydramine is a common cause of anticholinergic toxicity. Commonly known as minor tranquilisers or sleeping pills, benzodiazepines are prescribed for sedative, anxiolytic, hypnotic, and anticonvulsant purposes. The best way to reverse the effects of a diazepam overdose is to administer an antidote called flumazenil. In severe cases, a diazepam overdose can be fatal. Although not a potentially life-threatening poisoning, benzodiazepine (BZD). In 2013, benzodiazepines were involved in 31% of the estimated 22,767 deaths from prescription drug overdose in the United States. Benzodiazepine overdose occurs when excessive amounts of benzodiazepine medications are taken. A diazepam overdose can cause a number of serious symptoms, including loss of consciousness, slow and shallow breathing, and seizures. However, combinations of high doses of benzodiazepines with alcohol, barbiturates, opioids or tricyclic antidepressants are particularly dangerous, and may lead to severe complications such as coma or death. Deaths from single-drug benzodiazepine overdoses occur infrequently, particularly after the point of hospital admission.
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